Enzyme Details

EC Classification

3.6.1.9

Enzyme name
(recommended)

nucleoside-triphosphate diphosphatase

Alternative names

dinucleotide nucleotidohydrolase
nucleotide pyrophosphatase
nucleotide-sugar pyrophosphatase
nucleoside-triphosphate diphosphohydrolase
nucleoside-triphosphate pyrophosphatase

Classification

Hydrolases

Acting on acid anhydrides

In phosphorous-containing anhydrides

Catalyses reactions

H2O + UTP <-> Diphosphate + UMP

ATP + H2O <-> Diphosphate + AMP

ADP + H2O <-> Phosphate + AMP

H2O + ADPribose <-> AMP + D-Ribose 1-phosphate

H2O + UDP <-> Phosphate + UMP

H2O + UDPglucose <-> UMP + D-Glucose 1-phosphate

H2O + Dinucleotide <-> 2 5'-Ribonucleotide

NAD+ + H2O <-> AMP + Nicotinamide nucleotide

H2O + FAD <-> AMP + Riboflavin-5-phosphate

H2O + 3'-Phosphoadenylyl sulfate <-> Adenosine 3',5'-bisphosphate + Sulfate

H2O + Deamino-NAD+ <-> AMP + Nicotinate D-ribonucleotide

H2O + Dephospho-CoA <-> AMP + 4'-Phosphopantetheine

H2O + Bis-4-nitrophenyl phosphate <-> 4-Nitrophenyl phosphate + p-Nitrophenol

H2O + ADP alpha-D-glucoside <-> AMP + alpha-D-Glucose 1-phosphate

H2O + p-Nitrophenylthymidine phosphate <-> dTMP + p-Nitrophenol

NADH + H2O <-> AMP + Reduced nicotinamide nucleotide

H2O + CDPglucose <-> CMP + D-Glucose 1-phosphate

H2O + GTP <-> Diphosphate + GMP

H2O + CTP <-> Diphosphate + CMP

H2O + dGTP <-> dGMP + Diphosphate

H2O + 8-oxo-dGTP <-> Diphosphate + 8-oxo-dGMP

H2O + XTP <-> Diphosphate + XMP

H2O + ITP <-> Diphosphate + IMP

H2O + dTTP <-> Diphosphate + Thiamine monophosphate

H2O + UTP <-> Diphosphate + UMP

H2O + ITP <-> Diphosphate + IMP

H2O + GTP <-> Diphosphate + GMP

H2O + dGTP <-> dGMP + Diphosphate

H2O + dITP <-> Phosphate + dIMP

H2O + XTP <-> Diphosphate + XMP

H2O + NTP <-> Diphosphate + Nucleotide

H2O + dITP <-> Diphosphate + dIMP

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 3.6.1.9