Enzyme Details

EC Classification

4.1.1.71

Enzyme name
(recommended)

2-oxoglutarate decarboxylase

Alternative names

2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)
oxoglutarate decarboxylase
alpha-ketoglutarate decarboxylase
alpha-ketoglutaric decarboxylase
oxoglutarate decarboxylase
pre-2-oxoglutarate decarboxylase
2-oxoglutarate carboxy-lyase

Classification

Lyases

Carbon-carbon lyases

carboxy-lyases

Catalyses reactions

2-Oxoglutarate <-> CO2 + Succinate semialdehyde

Thiamine diphosphate + 2-Oxoglutarate <-> CO2 + Succinate semialdehyde-thiamin diphosphate anion

H2O + 2-Oxoglutarate + Hexacyanoferrate(III) <-> CO2 + Succinate + Hexacyanoferrate(II)

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 4.1.1.71