Enzyme Details

EC Classification

4.1.3.17

Enzyme name
(recommended)

4-hydroxy-4-methyl-2-oxoglutarate aldolase

Alternative names

4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)
pyruvate aldolase
gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase
4-hydroxy-4-methyl-2-ketoglutarate aldolase
4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase

Classification

Lyases

Carbon-carbon lyases

Oxo-acid-lyases

Catalyses reactions

4-Carboxy-4-hydroxy-2-oxoadipate <-> Pyruvate + Oxaloacetate

4-Hydroxy-4-methyl-2-oxoglutarate <-> 2 Pyruvate

Parapyruvate <-> 2 Pyruvate

Oxaloacetate <-> Pyruvate + CO2

4-Hydroxy-2-oxoglutarate <-> Pyruvate + Glyoxylate

Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 4.1.3.17