Enzyme Details

EC Classification

4.1.3.39

Enzyme name
(recommended)

4-hydroxy-2-oxovalerate aldolase

Alternative names

4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming)
4-hydroxy-2-ketovalerate aldolase
HOA
DmpG
4-hydroxy-2-oxovalerate pyruvate-lyase
4-hydroxy-2-oxopentanoate pyruvate-lyase

Classification

Lyases

Carbon-carbon lyases

Oxo-acid-lyases

Catalyses reactions

Pyruvate + Acetaldehyde <-> 4-Hydroxy-2-oxopentanoate

Pyruvate + Propanal <-> 4-Hydroxy-2-oxohexanoate

4-Hydroxy-2-oxoheptanoate <-> Pyruvate + Butanal

Oxaloacetate <-> Pyruvate + CO2

2-Dehydro-3-deoxy-D-xylonate <-> Pyruvate + Glycolaldehyde

Pyruvate + 2-Methylpropanal <-> 4-Hydroxy-2-oxo-5-methylhexanoate

Pyruvate + Pentanal <-> 4-Hydroxy-2-oxooctanoate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 4.1.3.39