Enzyme Details

 EC Classification 4.2.1.22
 Enzyme name
(recommended)
cystathionine beta-synthase
 Alternative names L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)
serine sulfhydrase
beta-thionase
methylcysteine synthase
cysteine synthase
serine sulfhydrylase
L-serine hydro-lyase (adding homocysteine)
 Classification
Lyases
Carbon-oxygen lyases
Hydro-lyases
 Catalyses reactions
L-Serine <-> Pyruvate + NH3
L-Serine + Sulfide <-> H2O + L-Cysteine
H2O + L-Cystathionine <-> Pyruvate + NH3 + L-Homocysteine
L-Serine + L-Homocysteine <-> H2O + Cystathionine
L-Serine + L-Homocysteine <-> H2O + L-Cystathionine
L-Serine + Selenohomocysteine <-> H2O + Selenocystathionine
L-Cysteine + L-Homocysteine <-> Hydrogen sulfide + L-Cystathionine
O-Acetyl-L-serine + Sulfide <-> L-Cysteine + Acetate
L-Cysteine + 2-Mercaptoethanol <-> Hydrogen sulfide + S-(2-Hydroxyethyl)-L-cysteine
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 4.2.1.22



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