Enzyme Details

EC Classification

4.2.1.9

Enzyme name
(recommended)

dihydroxy-acid dehydratase

Alternative names

alpha,beta-dihydroxyacid dehydratase
2,3-dihydroxy-3-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming)
acetohydroxyacid dehydratase
2,3-dihydroxyisovalerate dehydratase
alpha,beta-dihydroxyisovalerate dehydratase
dihydroxy acid dehydrase
DHAD
2,3-dihydroxy-acid hydro-lyase

Classification

Lyases

Carbon-oxygen lyases

Hydro-lyases

Catalyses reactions

2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline

(R)-2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline

(R)-2,3-Dihydroxy-3-methylpentanoate <-> H2O + (R)-2-Oxo-3-methylpentanoate

Threonate <-> H2O + 4-Hydroxy-2-oxobutanoic acid

D-Erythronic acid <-> H2O + 4-Hydroxy-2-oxobutanoic acid

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 4.2.1.9