Enzyme Details

EC Classification

4.4.1.11

Enzyme name
(recommended)

methionine gamma-lyase

Alternative names

L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)
L-methioninase
methionine lyase
methioninase
methionine dethiomethylase
L-methionine gamma-lyase
L-methionine methanethiol-lyase (deaminating)

Classification

Lyases

Carbon-sulfur lyases

Catalyses reactions

H2O + L-Methionine <-> NH3 + 2-Oxobutyrate + Methanethiol

H2O + L-Cysteine <-> Pyruvate + NH3 + Hydrogen sulfide

H2O + Selenomethionine <-> NH3 + 2-Oxobutyrate + Methaneselenol

H2O + O-Acetyl-L-serine <-> Pyruvate + NH3 + Acetate

H2O + Homocysteine <-> NH3 + 2-Oxobutyrate + Hydrogen sulfide

H2O + Trifluoromethionine <-> NH3 + 2-Oxobutyrate + Trifluoromethanethiol

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 4.4.1.11