| EC Classification |
5.3.3.1
|
Enzyme name
(recommended) |
steroid Delta-isomerase |
| Alternative names |
3-oxosteroid Delta5-Delta4-isomerase
hydroxysteroid isomerase
steroid isomerase
Delta5-ketosteroid isomerase
Delta5(or Delta4)-3-keto steroid isomerase
Delta5-steroid isomerase
3-oxosteroid isomerase
Delta5-3-keto steroid isomerase
Delta5-3-oxosteroid isomerase
|
| Classification |
| Isomerases |
| Intramolecular oxidoreductases |
| Transposing C=C Bonds |
|
| Catalyses reactions
|
| NAD+ + 3beta-Hydroxyandrost-5-en-17-one <-> NADH + H+ + Androst-4-ene-3,17-dione |
| NADP+ + 3beta-Hydroxyandrost-5-en-17-one <-> H+ + NADPH + Androst-4-ene-3,17-dione |
| NAD+ + Pregnenolone <-> NADH + H+ + Progesterone |
| NADP+ + Pregnenolone <-> H+ + NADPH + Progesterone |
| NADH + H+ + Testosterone <-> NAD+ + Androst-5-ene-3beta,17beta-diol |
| 3-Oxo-delta5-steroid <-> 3-Oxo-delta4-steroid |
| NADH + H+ + Cortisol <-> NAD+ + 11beta,17alpha,21-Trihydroxypregnenolone |
| H+ + NADPH + Cortisol <-> NADP+ + 11beta,17alpha,21-Trihydroxypregnenolone |
| NAD+ + 17alpha-Hydroxypregnenolone <-> NADH + H+ + 17alpha-Hydroxyprogesterone |
| NADP+ + 17alpha-Hydroxypregnenolone <-> H+ + NADPH + 17alpha-Hydroxyprogesterone |
| NAD+ + 21-Hydroxypregnenolone <-> NADH + H+ + 11-Deoxycorticosterone |
| NADP+ + 21-Hydroxypregnenolone <-> H+ + NADPH + 11-Deoxycorticosterone |
| NADH + H+ + 16alpha-Hydroxyandrost-4-ene-3,17-dione <-> NAD+ + 16alpha-Hydroxydehydroepiandrosterone |
| H+ + NADPH + 16alpha-Hydroxyandrost-4-ene-3,17-dione <-> NADP+ + 16alpha-Hydroxydehydroepiandrosterone |
| NADH + H+ + 11-Deoxycortisol <-> NAD+ + 17alpha,21-Dihydroxypregnenolone |
| H+ + NADPH + 11-Deoxycortisol <-> NADP+ + 17alpha,21-Dihydroxypregnenolone |
| Androst-5-ene-3,17-dione <-> Androst-4-ene-3,17-dione |
|
| External links
|
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
|
|
View all entries for EC Class:
5.3.3.1
|
