Enzyme Details
EC Classification
6.3.1.2
Enzyme name
(recommended)
glutamate---ammonia ligase
Alternative names
L-glutamate:ammonia ligase (ADP-forming)
glutamine synthetase
glutamylhydroxamic synthetase
L-glutamine synthetase
Classification
Ligases
Forming carbon-nitrogen bonds
Acid-D-ammonia (or amine) ligases (amide synthases)
Catalyses reactions
ATP + L-Glutamate + NH3 <-> ADP + Phosphate + L-Glutamine
ATP + L-Glutamate + Methylamine <-> ADP + Phosphate + N5-Methyl-L-glutamine
ATP + L-Glutamate + Ethylamine <-> ADP + Phosphate + N5-Ethyl-L-glutamine
ATP + NH3 + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine <-> ADP + Phosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl-L-lysyl-D-alanyl-D-alanine
ATP + NH3 + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <-> ADP + Phosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
ATP + NH3 + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine <-> ADP + Phosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
L-Glutamine + Hydroxylamine <-> NH3 + L-gamma-Glutamyl hydroxamate
ATP + L-Glutamate + Hydroxylamine <-> ADP + Phosphate + L-gamma-Glutamyl hydroxamate
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
6.3.1.2
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