Enzyme Details

EC Classification

6.3.2.1

Enzyme name
(recommended)

pantoate---beta-alanine ligase

Alternative names

(R)-pantoate:beta-alanine ligase (AMP-forming)
pantothenate synthetase
pantoate activating enzyme
pantoic-activating enzyme
D-pantoate:beta-alanine ligase (AMP-forming)

Classification

Ligases

Forming carbon-nitrogen bonds

Acid--amino-acid ligases (peptide synthases)

Catalyses reactions

ATP + beta-Alanine + (R)-Pantoate <-> Diphosphate + AMP + (R)-Pantothenate

ATP + D-Pantoate <-> Diphosphate + Pantoyl adenylate

ATP + 4-Aminobutanoate + (R)-Pantoate <-> Diphosphate + AMP + Pantoyl-gamma-aminobutyric acid

ATP + (R)-Pantoate + 4-Amino-3-hydroxybutanoate <-> Diphosphate + AMP + Pantoyl-gamma-amino-beta-hydroxybutyric acid

ATP + Cysteamine + (R)-Pantoate <-> Diphosphate + AMP + Pantoyl-beta-mercaptoethylamine

ATP + Taurine + (R)-Pantoate <-> Diphosphate + AMP + Pantoyltaurine

ATP + Methylamine + (R)-Pantoate <-> Diphosphate + AMP + Pantoylmethylamine

ATP + Glycolate + (R)-Pantoate <-> Unknown + Diphosphate + AMP

ATP + Glycine + (R)-Pantoate <-> Diphosphate + AMP + Pantoylglycine

ATP + Ethylamine + (R)-Pantoate <-> Diphosphate + AMP + Pantoylethylamine

ATP + (R)-Pantoate + Carbamate <-> Diphosphate + AMP + Pantoylcarbamate

ATP + 5-Aminopentanoate + (R)-Pantoate <-> Diphosphate + AMP + Pantoyl-5-aminovaleric acid

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.2.1