Enzyme Details

 EC Classification 6.3.2.10
 Enzyme name
(recommended)		 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
 Alternative names UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)
MurF synthetase
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase
UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase
uridine diphosphoacetylmuramoylpentapeptide synthetase
UDPacetylmuramoylpentapeptide synthetase
UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase
 Classification
Ligases
Forming carbon-nitrogen bonds
Acid--amino-acid ligases (peptide synthases)
 Catalyses reactions
ATP + D-Alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
ATP + D-Alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine <-> ADP + Phosphate + UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)
ATP + D-Alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine
ATP + D-Alanyl-D-phenylalanine + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-phenylalanine
ATP + D-Alanyl-D-lactate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-lactate
ATP + D-Alanyl-D-2-hydroxybutanoate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-2-hydroxybutanoate
ATP + D-Alanyl-D-methionine + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminopimelate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-methionine
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 6.3.2.10



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