Enzyme Details
EC Classification
6.3.2.11
Enzyme name
(recommended)
carnosine synthase
Alternative names
L-histidine:beta-alanine ligase (ADP-forming)
carnosine synthetase
carnosine-anserine synthetase
homocarnosine-carnosine synthetase
carnosine-homocarnosine synthetase
L-histidine:beta-alanine ligase (AMP-forming) (incorrect)
Classification
Ligases
Forming carbon-nitrogen bonds
Acid--amino-acid ligases (peptide synthases)
Catalyses reactions
ATP + L-Lysine + beta-Alanine <-> Diphosphate + AMP + beta-Alanyl-L-lysine
ATP + L-Arginine + beta-Alanine <-> Diphosphate + AMP + beta-Alanyl-L-arginine
ATP + L-Histidine + beta-Alanine <-> Diphosphate + AMP + Carnosine
ATP + L-Histidine + 4-Aminobutanoate <-> Diphosphate + AMP + Homocarnosine
ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> H2O + Diphosphate + AMP + beta-Alanyl-N(pai)-methyl-L-histidine
ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> Diphosphate + AMP + beta-Alanyl-N(pai)-methyl-L-histidine
ATP + L-Histidine + beta-Alanine <-> ADP + Phosphate + Carnosine
ATP + L-Histidine + 4-Aminobutanoate <-> ADP + Phosphate + Homocarnosine
ATP + L-Lysine + beta-Alanine <-> ADP + Phosphate + beta-Alanyl-L-lysine
ATP + L-Ornithine + beta-Alanine <-> ADP + Phosphate + beta-Alanyl-L-ornithine
ATP + beta-Alanine + N(pai)-Methyl-L-histidine <-> ADP + Phosphate + beta-Alanyl-N(pai)-methyl-L-histidine
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
6.3.2.11
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