Enzyme Details

 EC Classification 6.3.2.4
 Enzyme name
(recommended)		 D-alanine---D-alanine ligase
 Alternative names D-alanine:D-alanine ligase (ADP-forming)
MurE synthetase [ambiguous]
alanine:alanine ligase (ADP-forming)
alanylalanine synthetase
 Classification
Ligases
Forming carbon-nitrogen bonds
Acid--amino-acid ligases (peptide synthases)
 Catalyses reactions
ATP + 2 D-Alanine <-> ADP + Phosphate + D-Alanyl-D-alanine
ATP + D-Alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
ATP + D-Alanine + D-Methionine <-> ADP + Phosphate + D-Alanyl-D-methionine
ATP + D-Alanine + Phenyllactate <-> ADP + Phosphate + D-Alanyl-D-phenyllactate
ATP + D-Alanine + D-Lactate <-> ADP + Phosphate + D-Alanyl-D-lactate
ATP + D-Alanine + D-Phenylalanine <-> ADP + Phosphate + D-Alanyl-D-phenylalanine
ATP + D-Alanine + D-Norvaline <-> ADP + Phosphate + D-Alanyl-D-norvaline
ATP + D-Alanine + 2-Hydroxyvalerate <-> ADP + Phosphate + D-Alanyl-D-2-hydroxyvalerate
ATP + D-Alanine + D-2-Hydroxybutanoate <-> ADP + Phosphate + D-Alanyl-D-2-hydroxybutanoate
ATP + D-Alanine + D-2-Hydroxyvalerate <-> ADP + Phosphate + D-Alanyl-D-2-hydroxyvalerate
ATP + D-Alanine + 2-Hydroxycaproate <-> ADP + Phosphate + D-Alanyl-D-2-hydroxycaproate
ATP + D-Alanine + 2-Hydroxybutyrate <-> ADP + Phosphate + D-Alanyl-D-2-hydroxybutanoate
ATP + D-Alanine + D-Norleucine <-> ADP + Phosphate + D-Alanyl-D-norleucine
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + D-Alanyl-D-serine <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-serine
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + D-Alanyl-D-threonine <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-threonine
ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + D-Alanyl-D-2-aminobutyrate <-> ADP + Phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-2-aminobutyrate
 External links Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop


View all entries for EC Class: 6.3.2.4



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