Enzyme Details

EC Classification

6.3.3.1

Enzyme name
(recommended)

phosphoribosylformylglycinamidine cyclo-ligase

Alternative names

2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)
phosphoribosylaminoimidazole synthetase
AIR synthetase
5'-aminoimidazole ribonucleotide synthetase
2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)

Classification

Ligases

Forming carbon-nitrogen bonds

Cyclo-ligases

Catalyses reactions

ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <-> ADP + Phosphate + Aminoimidazole ribotide

2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + Adenosine 5-O-(3-thiotriphosphate) <-> Phosphate + Aminoimidazole ribotide + Adenosine 5-O-(3-thiodiphosphate)

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.3.1