Enzyme Details

EC Classification

6.3.3.2

Enzyme name
(recommended)

5-formyltetrahydrofolate cyclo-ligase

Alternative names

5-formyltetrahydrofolate cyclo-ligase (ADP-forming)
5,10-methenyltetrahydrofolate synthetase
formyltetrahydrofolic cyclodehydrase
5-formyltetrahydrofolate cyclodehydrase

Classification

Ligases

Forming carbon-nitrogen bonds

Cyclo-ligases

Catalyses reactions

ATP + 5-Formyltetrahydrofolate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolate

ATP + (6S)-5-Formyltetrahydrofolyl-glutamate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-glutamate

ATP + 5-Formyltetrahydrofolyl-[Glu](5) <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-[Glu](5)

ATP + 5-Formyltetrahydrofolyl-glutamate <-> ADP + Phosphate + 5,10-Methenyltetrahydrofolyl-glutamate

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.3.2