Enzyme Details
EC Classification
6.3.4.2
Enzyme name
(recommended)
CTP synthase
Alternative names
UTP:ammonia ligase (ADP-forming)
UTP---ammonia ligase
cytidine triphosphate synthetase
uridine triphosphate aminase
cytidine 5'-triphosphate synthetase
Classification
Ligases
Forming carbon-nitrogen bonds
Other carbon--nitrogen ligases
Catalyses reactions
ATP + NH3 + UTP <-> ADP + Phosphate + CTP
ATP + H2O + L-Glutamine + UTP <-> ADP + Phosphate + L-Glutamate + CTP
H2O + L-Glutamine <-> L-Glutamate + NH3
H2O + L-gamma-Glutamyl hydrazide <-> L-Glutamate + Hydrazine
H2O + L-gamma-Glutamyl hydroxamate <-> L-Glutamate + Hydroxylamine
ATP + UTP + Hydrazine <-> ADP + Phosphate + N4-Amino-CTP
ATP + UTP + Hydroxylamine <-> ADP + Phosphate + N4-Hydroxyl-CTP
ATP + H2O + UTP + L-gamma-Glutamyl hydrazide <-> ADP + Phosphate + L-Glutamate + N4-Amino-CTP
ATP + H2O + UTP + L-gamma-Glutamyl hydroxamate <-> ADP + Phosphate + L-Glutamate + N4-Hydroxyl-CTP
ATP + H2O + L-Glutamine + dUTP <-> ADP + Phosphate + L-Glutamate + dCTP
H2O + L-Glutamine + UTP + Adenosine 5-O-(3-thiotriphosphate) <-> ADP + L-Glutamate + CTP + Thiophosphate
External links
Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop
View all entries for EC Class:
6.3.4.2
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