Enzyme Details

EC Classification

6.3.5.2

Enzyme name
(recommended)

GMP synthase (glutamine-hydrolysing)

Alternative names

xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
GMP synthetase (glutamine-hydrolysing)
guanylate synthetase (glutamine-hydrolyzing)
guanosine monophosphate synthetase (glutamine-hydrolyzing)
xanthosine 5'-phosphate amidotransferase
guanosine 5'-monophosphate synthetase

Classification

Ligases

Forming carbon-nitrogen bonds

Carbon--nitrogen ligases with glutamine as amido-N-donor

Catalyses reactions

ATP + NH3 + XMP <-> Diphosphate + AMP + GMP

ATP + H2O + L-Glutamine + XMP <-> L-Glutamate + Diphosphate + AMP + GMP

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.5.2