Enzyme Details

EC Classification

6.3.5.3

Enzyme name
(recommended)

phosphoribosylformylglycinamidine synthase

Alternative names

N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
phosphoribosylformylglycinamidine synthetase
formylglycinamide ribonucloetide amidotransferase
phosphoribosylformylglycineamidine synthetase
FGAM synthetase
FGAR amidotransferase
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)

Classification

Ligases

Forming carbon-nitrogen bonds

Carbon--nitrogen ligases with glutamine as amido-N-donor

Catalyses reactions

ATP + H2O + L-Glutamine + 5'-Phosphoribosyl-N-formylglycinamide <-> ADP + Phosphate + L-Glutamate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine

ATP + H2O + NH3 + 5'-Phosphoribosyl-N-formylglycinamide <-> ADP + Phosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine

External links

Expasy
KEGG
BRENDA
IntEnz (EBI)
IUBMB
Reactome
MetaCrop

View all entries for EC Class: 6.3.5.3