Enzyme Details

Enzyme (Recommended) Name	retinol dehydrogenase
Alternative names	retinol:NAD+ oxidoreductase retinol (vitamin A1) dehydrogenase MDR microsomal retinol dehydrogenase all-trans retinol dehydrogenase retinal reductase retinene reductase
EC Classification	1.1.1.105
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + Retinol <-> NADH + H+ + all-trans-Retinal NAD+ + 5alpha-Androstane-3alpha-ol-17-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione NADP+ + 5alpha-Androstane-3alpha-ol-17-one <-> H+ + NADPH + 5alpha-Androstane-3,17-dione NAD+ + 11-cis-Retinol <-> NADH + H+ + 11-cis-Retinal NADH + H+ + 5alpha-Androstane-17beta-ol-3-one <-> NAD+ + 5alpha-Androstane-3alpha,17beta-diol H+ + NADPH + 5alpha-Androstane-17beta-ol-3-one <-> NADP+ + 5alpha-Androstane-3alpha,17beta-diol H+ + NADPH + 13-cis-Retinal <-> NADP+ + 13-cis-Retinol H+ + NADPH + all-trans-Retinal <-> NADP+ + Retinol H+ + NADPH + 9-cis-Retinal <-> NADP+ + 9-cis-Retinol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
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