Enzyme Details

Enzyme (Recommended) Name	21-hydroxysteroid dehydrogenase (NADP+)
Alternative names	21-hydroxysteroid:NADP+ 21-oxidoreductase 21-hydroxy steroid dehydrogenase 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) NADP+-21-hydroxysteroid dehydrogenase 21-hydroxysteroid dehydrogenase (NADP+)
EC Classification	1.1.1.151
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	H+ + NADPH + Pregnan-21-al <-> NADP+ + Pregnan-21-ol H+ + NADPH + 21-Dehydrocortisone <-> NADP+ + Cortisone H+ + NADPH + 21-Dehydrocortisol <-> NADP+ + Cortisol H+ + NADPH + 21-Dehydro-11-deoxycortisol <-> NADP+ + 11-Deoxycortisol H+ + NADPH + 21-Dehydro-delta1-cortisol <-> NADP+ + delta1-Cortisol H+ + NADPH + 21-Dehydro-11-deoxycorticosterone <-> NADP+ + 11-Deoxycorticosterone H+ + NADPH + 21-Dehydrocorticosterone <-> NADP+ + Corticosterone
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.151