Enzyme Details

Enzyme (Recommended) Name	7alpha-hydroxysteroid dehydrogenase
Alternative names	7alpha-hydroxysteroid:NAD+ 7-oxidoreductase 7alpha-hydroxy steroid dehydrogenase 7alpha-HSDH
EC Classification	1.1.1.159
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate <-> NADH + H+ + 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholanate NADP+ + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate <-> H+ + NADPH + 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholanate NADP+ + Chenodeoxycholate <-> H+ + NADPH + 3alpha-Hydroxy-7-oxo-5beta-cholanate NAD+ + Chenodeoxycholate <-> NADH + H+ + 3alpha-Hydroxy-7-oxo-5beta-cholanate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.159