Enzyme Details

Enzyme (Recommended) Name	tropinone reductase I
Alternative names	tropine:NADP+ 3alpha-oxidoreductase tropine dehydrogenase tropinone reductase (ambiguous) TR-I
EC Classification	1.1.1.206
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NADP+ + Tropine <-> H+ + NADPH + Tropinone H+ + NADPH + Nortropinone <-> NADP+ + Nortropine H+ + NADPH + Quinuclidinone <-> NADP+ + Quinuclidin-2-ol H+ + NADPH + N-Propylpiperidin-4-one <-> NADP+ + N-Propylpiperidin-4-ol H+ + NADPH + N-Methyl-4-piperidone <-> NADP+ + N-Methylpiperidin-4-ol H+ + NADPH + 3-Methylcyclohexanone <-> NADP+ + 3-Methylcyclohexanol H+ + NADPH + 4-Methylcyclohexanone <-> NADP+ + 4-Methylcyclohexanol H+ + NADPH + 8-Thiabicyclo[3.2.1]octan-3-one <-> NADP+ + 8-Thiabicyclo[3.2.1]octan-3-ol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.206