Enzyme Details

Enzyme (Recommended) Name	3beta(or 20alpha)-hydroxysteroid dehydrogenase
Alternative names	3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase progesterone reductase dehydrogenase, 3beta,20alpha-hydroxy steroid 3beta,20alpha-hydroxysteroid oxidoreductase
EC Classification	1.1.1.210
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	H+ + NADPH + 5alpha-Androstane-17beta-ol-3-one <-> NADP+ + 5alpha-Androstan-3beta,17beta-diol NAD+ + 5alpha-Androstane-3alpha-ol-17-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione NAD+ + Epiandrosterone <-> NADH + H+ + 5alpha-Androstane-3,17-dione NAD+ + 3alpha-Hydroxy-5beta-androstan-17-one <-> NADH + H+ + 5beta-Androstane-3,17-dione NAD+ + 5alpha-Androstane-17beta-ol-3-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione NAD+ + 3beta-Hydroxy-5beta-androstan-17-one <-> NADH + H+ + 5beta-Androstane-3,17-dione NAD+ + Estradiol-17beta <-> NADH + H+ + Estrone NAD+ + Testosterone <-> NADH + H+ + Androst-4-ene-3,17-dione NAD+ + 20alpha-Hydroxy-4-pregnen-3-one <-> NADH + H+ + Progesterone H+ + NADPH + 5beta-Androstane-17beta-ol-3-one <-> NADP+ + 5beta-Androstane-3alpha,17beta-diol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
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