Enzyme Details

Enzyme (Recommended) Name	morphine 6-dehydrogenase
Alternative names	morphine:NAD(P)+ 6-oxidoreductase naloxone reductase reductase, naloxone
EC Classification	1.1.1.218
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + Morphine <-> NADH + H+ + Morphinone NADP+ + Morphine <-> H+ + NADPH + Morphinone NADP+ + Codeine <-> H+ + NADPH + 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one NAD+ + Normorphine <-> NADH + H+ + Normorphinone NAD+ + Ethylmorphine <-> NADH + H+ + Ethylmorphinone NAD+ + Nalorphine <-> NADH + H+ + Nalorphinone NAD+ + Dihydrocodeine <-> NADH + H+ + Hydrocodone NAD+ + Codeine <-> NADH + H+ + 7,8-Didehydro-4,5-epoxy-3-methoxy-17-methoxy-(5_)-morphinan-6-one NADP+ + Ethylmorphine <-> H+ + NADPH + Ethylmorphinone NADP+ + Dihydrocodeine <-> H+ + NADPH + Hydrocodone NADP+ + Nalorphine <-> H+ + NADPH + Nalorphinone NADP+ + Normorphine <-> H+ + NADPH + Normorphinone
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.218