Enzyme Details

Enzyme (Recommended) Name	3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
Alternative names	3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase 3alpha,17beta-hydroxy steroid dehydrogenase 3alpha(17beta)-HSD 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
EC Classification	1.1.1.239
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + Testosterone <-> NADH + H+ + Androst-4-ene-3,17-dione NAD+ + Estradiol-17beta <-> NADH + H+ + Estrone NAD+ + 5alpha-Androstane-17beta-ol-3-one <-> NADH + H+ + 5alpha-Androstane-3,17-dione NAD+ + 5beta-Androstane-3alpha,17beta-diol <-> NADH + H+ + 3alpha-Hydroxy-5beta-androstan-17-one NAD+ + 5alpha-Androstane-3alpha,17beta-diol <-> NADH + H+ + 5alpha-Androstan-3alpha-ol-17-one NAD+ + 5beta-Androstane-17beta-ol-3-one <-> NADH + H+ + 5beta-Androstane-3,17-dione NADH + H+ + Estrone 3-sulfate <-> NAD+ + Estradiol-17beta 3-sulfate H+ + NADPH + 5alpha-Androstane-3alpha-ol-17-one <-> NADP+ + 5alpha-Androstane-3alpha,17beta-diol NADP+ + 5alpha-Androstane-17beta-ol-3-one <-> H+ + NADPH + 5alpha-Androstane-3,17-dione NADP+ + Testosterone <-> H+ + NADPH + Androst-4-ene-3,17-dione NAD+ + Testosterone <-> NADH + H+ + Androst-4-ene-3,17-dione
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.239