Enzyme Details

Enzyme (Recommended) Name	1-deoxy-D-xylulose-5-phosphate reductoisomerase
Alternative names	2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing) DXP-reductoisomerase 1-deoxy-D-xylulose-5-phosphate isomeroreductase 2-C-methyl-D-erythritol 4-phosphate (MEP) synthase
EC Classification	1.1.1.267
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NADP+ + 2-C-Methyl-D-erythritol 4-phosphate <-> H+ + NADPH + 1-Deoxy-D-xylulose 5-phosphate H+ + NADPH + 1-Fluoro-1-deoxy-D-xylulose 5-phosphate <-> NADP+ + 2-C-Fluoromethyl-D-erythritol 4-phosphate H+ + NADPH + 1,2-Dideoxy-D-hexulose 6-phosphate <-> NADP+ + 2-C-Ethyl-D-erythritol 4-phosphate H+ + NADPH + 1,1-Difluoro-1-deoxy-D-xylulose 5-phosphate <-> NADP+ + 2-C-Difluoromethyl-D-erythritol 4-phosphate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
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