Enzyme Details

Enzyme (Recommended) Name	GDP-L-fucose synthase
Alternative names	GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing) GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase
EC Classification	1.1.1.271
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + GDP-L-fucose <-> NADH + H+ + GDP-4-dehydro-D-rhamnose NADP+ + GDP-L-fucose <-> H+ + NADPH + GDP-4-dehydro-D-rhamnose GDP-4-dehydro-D-rhamnose + GDP-fucose synthase <-> Enzyme-ligand complex GDP-fucose synthase + GDP-fucose <-> Enzyme-ligand complex GDP + GDP-fucose synthase <-> Enzyme-ligand complex NADPH + GDP-fucose synthase <-> Enzyme-ligand complex NADP+ + GDP-fucose synthase <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.271