Enzyme Details

Enzyme (Recommended) Name	2-hydroxymethylglutarate dehydrogenase
Alternative names	(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase HgD
EC Classification	1.1.1.291
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + (S)-2-(Hydroxymethyl)glutarate <-> NADH + H+ + (S)-2-Formylglutarate NAD+ + L-Serine <-> NADH + H+ + L-2-Amino-3-oxopropionate NAD+ + L-Glycerate <-> NADH + H+ + 3-Hydroxypyruvate NAD+ + (S)-3-Hydroxyisobutyrate <-> NADH + H+ + (S)-Methylmalonate semialdehyde NAD+ + 2-(Hydroxymethyl)glutarate <-> NADH + 2-Formylglutarate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.291