Enzyme Details

Enzyme (Recommended) Name	hydroxymethylglutaryl-CoA reductase (NADPH)
Alternative names	(R)-mevalonate:NADP+ oxidoreductase (CoA-acylating) hydroxymethylglutaryl coenzyme A reductase (reduced nicotinamide adenine dinucleotide phosphate) 3-hydroxy-3-methylglutaryl-CoA reductase beta-hydroxy-beta-methylglutaryl coenzyme A reductase hydroxymethylglutaryl CoA reductase (NADPH) S-3-hydroxy-3-methylglutaryl-CoA reductase NADPH-hydroxymethylglutaryl-CoA reductase HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating-CoA) 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) hydroxymethylglutaryl-CoA reductase (NADPH2)
EC Classification	1.1.1.34
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	2 NADP+ + Coenzyme A + (R)-Mevalonate <-> 2 H+ + 2 NADPH + 3-Hydroxy-3-methylglutaryl-CoA 2 NAD+ + Coenzyme A + Mevalonate <-> 2 NADH + 2 H+ + 3-Hydroxy-3-methylglutaryl-CoA
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.34