Enzyme Details

Enzyme (Recommended) Name	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
Alternative names	(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating) 'malic' enzyme pyruvic-malic carboxylase malate dehydrogenase (decarboxylating, NADP+) NADP+-linked decarboxylating malic enzyme NADP+-malic enzyme NADP+-specific malic enzyme NADP+-specific malate dehydrogenase malate dehydrogenase (NADP+, decarboxylating) L-malate:NADP+ oxidoreductase malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
EC Classification	1.1.1.40
Classification	Oxidoreductases Acting on the CH-OH group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + L-Malate <-> Pyruvate + NADH + H+ + CO2 NADP+ + L-Malate <-> Pyruvate + H+ + NADPH + CO2 Oxaloacetate <-> Pyruvate + CO2 Pyruvate + H+ + NADPH <-> NADP+ + L-Lactate Pyruvate + H+ + NADPH <-> NADP+ + Lactate Bromopyruvate + Malic enzyme <-> Enzyme-ligand complex NADPH + Malic enzyme <-> Enzyme-ligand complex NADPH + Alkylated malic enzyme <-> Enzyme-ligand complex Malic enzyme + 2',3'-Dialdehyde NADP+ <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.1.1.40