Enzyme Details

Enzyme (Recommended) Name	arachidonate 5-lipoxygenase
Alternative names	arachidonate:oxygen 5-oxidoreductase leukotriene-A4 synthase Delta5-lipoxygenase 5Delta-lipoxygenase arachidonic 5-lipoxygenase arachidonic acid 5-lipoxygenase C-5-lipoxygenase LTA synthase leukotriene A4 synthase
EC Classification	1.13.11.34
Classification	Oxidoreductases Acting on single donors with incorporation of molecular oxygen With incorporation of two atoms of oxygen
Catalyses reactions	O2 + Arachidonate <-> 5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate 5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate <-> H2O + Leukotriene A4 O2 + Eicosapentaenoic acid <-> 5-Hydroperoxy-6,8,11,14,17-eicosapentaenoate O2 + Arachidonate <-> H2O + Leukotriene A4
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.13.11.34