Enzyme Details

Enzyme (Recommended) Name	gentisate 1,2-dioxygenase
Alternative names	gentisate:oxygen 1,2-oxidoreductase (decyclizing) gentisate oxygenase 2,5-dihydroxybenzoate dioxygenase gentisate dioxygenase gentisic acid oxidase
EC Classification	1.13.11.4
Classification	Oxidoreductases Acting on single donors with incorporation of molecular oxygen With incorporation of two atoms of oxygen
Catalyses reactions	O2 + 2,5-Dihydroxybenzoate <-> 3-Maleylpyruvate O2 + 3-Methylgentisate <-> 4-Hydroxy-3-methyl-6-oxo-hepta-2,4-dienedioic acid O2 + 3-Bromogentisate <-> 3-Bromo-4-hydroxy-6-oxo-hepta-2,4-dienedioic acid O2 + 3-Isopropylgentisate <-> 4-Hydroxy-3-isopropyl-6-oxo-hepta-2,4-dienedioic acid
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.13.11.4