Enzyme Details

Enzyme (Recommended) Name	nitric oxide dioxygenase
Alternative names	nitric oxide,NAD(P)H:oxygen oxidoreductase
EC Classification	1.14.12.17
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
Catalyses reactions	NADH + H+ + H2O2 <-> NAD+ + 2 H2O NADH + 2 O2 + 2 Nitric oxide <-> NAD+ + H+ + 2 Nitrate NADPH + 2 O2 + 2 Nitric oxide <-> H+ + NADP+ + 2 Nitrate NADH + H+ + Cumene hydroperoxide <-> NAD+ + H2O + 2-Phenyl-2-propanol NADH + H+ + t-Butylhydroperoxide <-> NAD+ + H2O + t-Butanol NADH + H+ + (9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoate <-> NAD+ + H2O + 13(S)-HODE NAD+ + 2 Fe2+ <-> NADH + H+ + 2 Fe3+ NADH + S-Nitrosoglutathione <-> NAD+ + Glutathione sulfinamide NADH + H+ + Cytochrome c <-> NAD+ + Reduced cytochrome c NADH + H+ + Nitrite <-> NAD+ + H2O + Nitric oxide
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.12.17