Enzyme Details

Enzyme (Recommended) Name	phenol 2-monooxygenase
Alternative names	phenol,NADPH:oxygen oxidoreductase (2-hydroxylating) phenol hydroxylase phenol o-hydroxylase
EC Classification	1.14.13.7
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Catalyses reactions	2 NADH + 2 H+ + O2 <-> 2 NAD+ + 2 H2O H+ + NADPH + O2 + Phenol <-> H2O + NADP+ + Catechol H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + o-Cresol H+ + NADPH + O2 + Toluene <-> H2O + NADP+ + 3-Cresol H+ + NADPH + O2 + 3-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene H+ + NADPH + O2 + 4-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene H+ + NADPH + O2 + o-Cresol <-> H2O + NADP+ + 2,3-Dihydroxytoluene H+ + NADPH + O2 + Resorcinol <-> H2O + NADP+ + Benzene-1,2,4-triol NAD+ + Reduced FMN <-> NADH + H+ + Riboflavin-5-phosphate H+ + NADPH + O2 + Hydroquinone <-> H2O + NADP+ + Benzene-1,2,4-triol NADH + H+ + 2,6-Dichloroindophenol <-> NAD+ + Reduced 2,6-dichlorophenolindophenol NADH + H+ + 3-Acetylpyridine-adenine dinucleotide <-> NAD+ + Reduced 3-acetylpyridine-adenine dinucleotide NADH + H+ + FAD <-> NAD+ + FADH2 NADH + H+ + Riboflavin <-> NAD+ + Reduced riboflavin H+ + NADPH + FAD <-> NADP+ + FADH2
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.13.7