Enzyme Details

Enzyme (Recommended) Name	With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
EC Classification	1.14.14
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions	H+ + NADPH + O2 + Phenacetin <-> H2O + Ethanol + NADP+ + Acetaminophen H+ + NADPH + O2 + Omeprazole <-> Unknown + H2O + NADP+ H+ + NADPH + O2 + Chlorzoxazone <-> H2O + NADP+ + 6-Hydroxy-chlorzoxazone H+ + NADPH + O2 + Flucloxacillin <-> H2O + NADP+ + 5-Hydroxymethylflucloxacillin H+ + NADPH + O2 + Diclofenac <-> H2O + NADP+ + 4'-Hydroxydiclofenac 2 NADH + H+ + O2 + 2,4,5-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,5-Dichlorohydroquinone 2 NADH + H+ + O2 + 2,4,6-Trichlorophenol <-> Cl- + 2 NAD+ + OH- + 2,6-Dichlorohydroquinone FADH2 + FADH2-dependent monooxygenase <-> Enzyme-FADH2 complex H+ + NADPH + O2 + Geissoschizine <-> 2 H2O + NADP+ + Polyneuridine aldehyde H+ + NADPH + O2 + Tetrahydroalstonine <-> 2 H2O + NADP+ + Alstonine H+ + NADPH + O2 + Tabersonine <-> H2O + NADP+ + Lochnericine Guaiacol + GcoA <-> Enzyme-ligand complex 3-Methoxycatechol + GcoA <-> Enzyme-ligand complex Anisole + GcoA <-> Enzyme-ligand complex Guaethol + GcoA <-> Enzyme-ligand complex 2-Methylanisole + GcoA <-> Enzyme-ligand complex 4-Hydroxy-3-methoxy-benzaldehyde + GcoA <-> Enzyme-ligand complex 2,6-Dimethoxyphenol + GcoA <-> Enzyme-ligand complex H+ + NADPH + O2 + 3beta-Hydroxyandrost-5-en-17-one <-> H2O + NADP+ + 3beta,7alpha-Dihydroxyandrost-5-en-17-one H+ + NADPH + O2 + Pregnenolone <-> H2O + NADP+ + 7alpha-Hydroxypregnenolone H+ + NADPH + O2 + Estradiol-17beta <-> H2O + NADP+ + 7alpha-Hydroxyestradiol NADH + H+ + O2 + 4-Hydroxyphenylacetate <-> NAD+ + H2O + 3,4-Dihydroxyphenylacetate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.14