Enzyme Details

Enzyme (Recommended) Name	steroid 21-monooxygenase
EC Classification	1.14.14.16
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions	H+ + NADPH + O2 + Progesterone <-> H2O + NADP+ + 11-Deoxycorticosterone H+ + NADPH + O2 + 17alpha-Hydroxyprogesterone <-> H2O + NADP+ + 11-Deoxycortisol Progesterone + CYP21A2 <-> Enzyme-ligand complex 17alpha-Hydroxyprogesterone + CYP21A2 <-> Enzyme-ligand complex 11-Deoxycorticosterone + CYP21A2 <-> Enzyme-ligand complex 11-Deoxycortisol + CYP21A2 <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.14.16