Enzyme Details

Enzyme (Recommended) Name vitamin D 25-hydroxylase
Alternative names calciol,NADPH:oxygen oxidoreductase (25-hydroxylating)
vitamin D2 25-hydroxylase
vitamin D3 25-hydroxylase
CYP2R1
EC Classification 1.14.14.24
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions
H+ + NADPH + O2 + Vitamin D3 <-> H2O + NADP+ + Calcidiol
H+ + NADPH + O2 + Vitamin D2 <-> H2O + NADP+ + 25-Hydroxyvitamin D2
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.14.14.24