Enzyme Details

Enzyme (Recommended) Name	quinine 3-monooxygenase
Alternative names	quinine,NADPH:oxygen oxidoreductase quinine 3-hydroxylase
EC Classification	1.14.14.55
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions	H+ + NADPH + O2 + Quinine <-> H2O + NADP+ + 3-Hydroxyquinine H+ + NADPH + O2 + 7-Benzyloxyquinoline <-> H2O + NADP+ + Benzaldehyde + 7-Hydroxyquinoline H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 15beta-Hydroxytestosterone H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 1beta-Hydroxytestosterone H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 2beta-Hydroxytestosterone H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 6beta-Hydroxytestosterone H+ + NADPH + O2 + Carbamazepine <-> H2O + NADP+ + Carbamazepine-10,11-epoxide H+ + NADPH + O2 + Nevirapine <-> H2O + NADP+ + 2-Hydroxy-nevirapine NADPH + O2 + Pradefovir <-> H2O + NADP+ + Adefovir
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
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