Enzyme Details

Enzyme (Recommended) Name taurochenodeoxycholate 6alpha-hydroxylase
Alternative names taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating)
CYP3A4
CYP4A21
taurochenodeoxycholate 6alpha-monooxygenase
EC Classification 1.14.14.57
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Catalyses reactions
L-Cysteine + Sulfite <-> Hydrogen sulfide + L-Cysteate
H+ + NADPH + O2 + Testosterone <-> H2O + NADP+ + 6beta-Hydroxytestosterone
H+ + NADPH + O2 + 3,5-Dihydroxy-4'-O-methoxystilbene <-> H2O + NADP+ + Trihydroxy-4'-O-methoxystilbene
H+ + NADPH + O2 + 5,4'-Dihydroxy-3-O-methoxystilbene <-> H2O + NADP+ + Trihydroxy-3-O-methoxystilbene
H+ + NADPH + O2 + Piceid <-> H2O + NADP+ + Tetrahydroxystilbene-3-beta-monoglucoside
H+ + NADPH + O2 + 3,4',5-Trihydroxystilbene <-> H2O + NADP+ + Tetrahydroxystilbene
H+ + NADPH + O2 + Resveratroloside <-> H2O + NADP+ + Trihydroxystilbene-4'-O-beta-D-glucopyranoside
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.14.14.57