Enzyme Details

Enzyme (Recommended) Name	tyrosine 3-monooxygenase
Alternative names	L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) L-tyrosine hydroxylase tyrosine 3-hydroxylase tyrosine hydroxylase
EC Classification	1.14.16.2
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With reduced pteridine as one donor, and incorporation of one atom of oxygen
Catalyses reactions	L-Tyrosine + O2 + Tetrahydrobiopterin <-> H2O + 6,7-Dihydrobiopterin + L-Dopa L-Tyrosine + O2 + Tetrahydrobiopterin <-> L-Dopa + 4a-Hydroxytetrahydrobiopterin L-Tyrosine + O2 + 6-Methyltetrahydropterin <-> L-Dopa + 4-Hydroxy-6-methyltetrahydropterin L-Phenylalanine + O2 + 6-Methyltetrahydropterin <-> H2O + L-Tyrosine + 6-Methyldihydropterin O2 + Tyramine <-> H2O + Dopamine
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.16.2