Enzyme Details

Enzyme (Recommended) Name	dopamine beta-monooxygenase
Alternative names	3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) dopamine beta-hydroxylase MDBH (membrane-associated dopamine beta-monooxygenase) SDBH (soluble dopamine beta-monooxygenase) dopamine-B-hydroxylase oxygenase, dopamine beta-mono- 3,4-dihydroxyphenethylamine beta-oxidase 4-(2-aminoethyl)pyrocatechol beta-oxidase dopa beta-hydroxylase dopamine beta-oxidase dopamine hydroxylase phenylamine beta-hydroxylase (3,4-dihydroxyphenethylamine)beta-mono-oxygenase DbetaM
EC Classification	1.14.17.1
Classification	Oxidoreductases Acting on paired donors with incorporation of molecular oxygen With ascorbate as one donor, and incorporation of one atom of oxygen
Catalyses reactions	O2 + L-Ascorbate + Dopamine <-> H2O + L-Noradrenaline + Dehydroascorbate O2 + Tyramine + N-(4-Chlorophenyl)-N'-hydroxyguanidine <-> H2O + 1-(4-Hydroxyphenyl)-2-aminoethanol + N-(4-Chlorophenyl)-N'-nitrosoimine O2 + Tyramine + N-(4-Methoxyphenyl)-N'-hydroxyguanidine <-> H2O + 1-(4-Hydroxyphenyl)-2-aminoethanol + N-(4-Methoxyphenyl)-N'-nitrosoimine O2 + L-Ascorbate + 4-(Trifluoromethyl)phenethylamine <-> H2O + Dehydroascorbate + 4-(Trifluoromethyl)phenylethanolamine O2 + L-Ascorbate + 2-Phenylethylamine <-> H2O + Phenylethanolamine + Dehydroascorbate O2 + L-Ascorbate + Tyramine <-> H2O + Dehydroascorbate + 1-(4-Hydroxyphenyl)-2-aminoethanol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.14.17.1