Enzyme Details

Enzyme (Recommended) Name 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
Alternative names 7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating)
7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase
CYP12
sterol 12alpha-hydroxylase (ambiguous)
HCO 12alpha-hydroxylase
EC Classification 1.14.18.8
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With another compound as one donor, and incorporation of one atom of oxygen
Catalyses reactions
H+ + NADPH + O2 + 7alpha-Hydroxycholest-4-en-3-one <-> H2O + NADP+ + 7alpha,12alpha-Dihydroxycholest-4-en-3-one
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.14.18.8