Enzyme Details

Enzyme (Recommended) Name	[methionine synthase] reductase
Alternative names	[methionine synthase]-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase methionine synthase cob(II)alamin reductase (methylating) methionine synthase reductase [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing)
EC Classification	1.16.1.8
Classification	Oxidoreductases Oxidizing metal ions With NAD(+) or NADP(+) as acceptor
Catalyses reactions	H+ + NADPH + S-Adenosyl-L-methionine + [Methionine synthase]-cob(II)alamin <-> NADP+ + S-Adenosyl-L-homocysteine + [Methionine synthase]-methylcob(I)alamin H+ + NADPH + 2 Ferricytochrome c <-> NADP+ + 2 Ferrocytochrome c NADH + Cytochrome c3+ <-> NAD+ + H+ + Cytochrome c2+ NADPH + Cytochrome c3+ <-> H+ + NADP+ + Cytochrome c2+ NADP+ + MSR <-> Enzyme-ligand complex Adenosine 2',5'-bisphosphate + MSR <-> Enzyme-ligand complex Adenosine 2',5'-bisphosphate + FADD <-> Enzyme-ligand complex NADP+ + FADD <-> Enzyme-ligand complex
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.16.1.8