Enzyme Details

Enzyme (Recommended) Name	ribonucleoside-diphosphate reductase
Alternative names	2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase ribonucleotide reductase CDP reductase ribonucleoside diphosphate reductase UDP reductase ADP reductase nucleoside diphosphate reductase ribonucleoside 5'-diphosphate reductase ribonucleotide diphosphate reductase 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase RR
EC Classification	1.17.4.1
Classification	Oxidoreductases Acting on -CH(2) groups With a disulfide as acceptor
Catalyses reactions	H2O + Oxidized thioredoxin + dGDP <-> GDP + Reduced thioredoxin H2O + dADP + Oxidized thioredoxin <-> ADP + Reduced thioredoxin H2O + Oxidized thioredoxin + dUDP <-> UDP + Reduced thioredoxin H2O + Oxidized thioredoxin + dCDP <-> CDP + Reduced thioredoxin H2O + Oxidized thioredoxin + Deoxynucleoside diphosphate <-> Reduced thioredoxin + NDP CDP + Reduced glutaredoxin <-> H2O + dCDP + Oxidized glutaredoxin CDP + 1,4-Dithiothreitol <-> H2O + dCDP + Oxidized dithiothreitol CTP + 1,4-Dithiothreitol <-> H2O + dCTP + Oxidized dithiothreitol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.17.4.1