Enzyme Details

Enzyme (Recommended) Name	ribonucleoside-triphosphate reductase
Alternative names	2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase ribonucleotide reductase 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase
EC Classification	1.17.4.2
Classification	Oxidoreductases Acting on -CH(2) groups With a disulfide as acceptor
Catalyses reactions	H2O + Oxidized thioredoxin + Deoxynucleoside triphosphate <-> Reduced thioredoxin + NTP H2O + Oxidized thioredoxin + dCDP <-> CDP + Reduced thioredoxin H2O + Oxidized thioredoxin + dCTP <-> CTP + Reduced thioredoxin H2O + Oxidized thioredoxin + dUTP <-> UTP + Reduced thioredoxin H2O + dATP + Oxidized thioredoxin <-> ATP + Reduced thioredoxin H2O + Oxidized thioredoxin + dGTP <-> GTP + Reduced thioredoxin CTP + Dihydrolipoate <-> H2O + dCTP + Lipoate CDP + Dihydrolipoate <-> H2O + dCDP + Lipoate CMP + Dihydrolipoate <-> H2O + dCMP + Lipoate GTP + Dihydrolipoate <-> H2O + dGTP + Lipoate ATP + 1,4-Dithiothreitol <-> H2O + dATP + Oxidized dithiothreitol
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.17.4.2