Enzyme Details

Enzyme (Recommended) Name	2-oxoaldehyde dehydrogenase (NADP+)
Alternative names	2-oxoaldehyde:NADP+ 2-oxidoreductase alpha-ketoaldehyde dehydrogenase methylglyoxal dehydrogenase NADP+-linked alpha-ketoaldehyde dehydrogenase 2-ketoaldehyde dehydrogenase NADP+-dependent alpha-ketoaldehyde dehydrogenase 2-oxoaldehyde dehydrogenase (NADP+)
EC Classification	1.2.1.49
Classification	Oxidoreductases Acting on the aldehyde or oxo group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	H2O + NADP+ + 2-Oxoaldehyde <-> H+ + NADPH + 2-Oxo acid H2O + NADP+ + Methylglyoxal <-> Pyruvate + H+ + NADPH NADP+ + L-Lactaldehyde <-> H+ + NADPH + Methylglyoxal H2O + NADP+ + Glyoxal <-> H+ + NADPH + Glyoxylate H2O + NADP+ + Hydroxypyruvaldehyde <-> H+ + NADPH + 3-Hydroxypyruvate H2O + NADP+ + Phenylglyoxal <-> H+ + NADPH + alpha-Oxo-benzeneacetic acid H2O + NADP+ + 2-Keto-3-deoxy-D-glucose <-> H+ + NADPH + 2-Dehydro-3-deoxy-D-gluconate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.2.1.49