Enzyme Details

Enzyme (Recommended) Name thyroxine 5'-deiodinase
Alternative names acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)
diiodothyronine 5'-deiodinase
iodothyronine 5'-deiodinase
iodothyronine outer ring monodeiodinase
type I iodothyronine deiodinase
type II iodothyronine deiodinase
thyroxine 5-deiodinase
L-thyroxine iodohydrolase (reducing)
EC Classification 1.21.99.4
Classification
Oxidoreductases
Acting on X-H and Y-H to form an X-Y bond
With other acceptors
Catalyses reactions
L-Thyroxine + Reduced acceptor <-> H+ + I- + Acceptor + Triiodothyronine
Reduced acceptor + 3,3',5'-Triiodothyronine <-> H+ + I- + Acceptor + 3,3'-Diiodothyronine
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.21.99.4