Enzyme Details

Enzyme (Recommended) Name	valine dehydrogenase (NADP+)
Alternative names	L-valine:NADP+ oxidoreductase (deaminating) valine dehydrogenase (nicotinanide adenine dinucleotide phosphate) valine dehydrogenase (NADP+)
EC Classification	1.4.1.8
Classification	Oxidoreductases Acting on the CH-NH(2) group of donors With NAD(+) or NADP(+) as acceptor
Catalyses reactions	NAD+ + H2O + L-Alanine <-> Pyruvate + NADH + H+ + NH3 NAD+ + H2O + L-Leucine <-> NADH + H+ + NH3 + 4-Methyl-2-oxopentanoate H2O + L-Valine + NADP+ <-> H+ + NADPH + NH3 + alpha-Ketovaline NAD+ + H2O + L-Valine <-> NADH + H+ + NH3 + alpha-Ketovaline NAD+ + H2O + L-Norleucine <-> NADH + H+ + NH3 + 2-Oxohexanoate NAD+ + H2O + L-Norvaline <-> NADH + H+ + NH3 + 2-Oxopentanoate NAD+ + H2O + L-Isoleucine <-> NADH + H+ + NH3 + 3-Methyl-2-oxopentanoate NAD+ + H2O + L-alpha-Aminobutyrate <-> NADH + H+ + NH3 + 2-Oxobutyrate
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 1.4.1.8