Enzyme Details

Enzyme (Recommended) Name saccharopine dehydrogenase (NADP+, L-lysine-forming)
Alternative names N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
lysine-2-oxoglutarate reductase
lysine-ketoglutarate reductase
L-lysine-alpha-ketoglutarate reductase
lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)
saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase
6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
EC Classification 1.5.1.8
Classification
Oxidoreductases
Acting on the CH-NH group of donors
With NAD(+) or NADP(+) as acceptor
Catalyses reactions
H2O + NADP+ + N6-(L-1,3-Dicarboxypropyl)-L-lysine <-> H+ + L-Lysine + NADPH + 2-Oxoglutarate
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.5.1.8