Enzyme Details

Enzyme (Recommended) Name	amine N-methyltransferase
Alternative names	S-adenosyl-L-methionine:amine N-methyltransferase nicotine N-methyltransferase tryptamine N-methyltransferase arylamine N-methyltransferase tryptamine methyltransferase
EC Classification	2.1.1.49
Classification	Transferases Transferring one-carbon groups Methyltransferases
Catalyses reactions	S-Adenosyl-L-methionine + Tryptamine <-> S-Adenosyl-L-homocysteine + N-Methyltryptamine S-Adenosyl-L-methionine + Amine <-> S-Adenosyl-L-homocysteine + Methylated amine S-Adenosyl-L-methionine + Serotonin <-> S-Adenosyl-L-homocysteine + N-Methylserotonin S-Adenosyl-L-methionine + Desipramine <-> S-Adenosyl-L-homocysteine + Imipramine S-Adenosyl-L-methionine + Pyrazole <-> S-Adenosyl-L-homocysteine + 1-Methylpyrazole S-Adenosyl-L-methionine + 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline <-> S-Adenosyl-L-homocysteine + N-Methyl-7,8-dichloro-1,2,3,4-tetrahydroisoquinoline S-Adenosyl-L-methionine + Imidazole <-> S-Adenosyl-L-homocysteine + N-Methylimidazole S-Adenosyl-L-methionine + Aniline <-> S-Adenosyl-L-homocysteine + N-Methylaniline S-Adenosyl-L-methionine + Norharmane <-> S-Adenosyl-L-homocysteine + N-Methylnorharmane
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 2.1.1.49